According to the Centers for Disease Control and Prevention (CDC), an estimated 50 million adults in the U.S. suffered from chronic pain in 2016, and according to the Substance Abuse and Mental Health Services Administration (SAMHSA), an estimated 10.3 million people in the U.S. ages 12 and older misused opioids in 2018. As such, the National Institutes of Health (NIH) have announced the awarding of $945 million in research grants to tackle the national opioid crisis through NIH HEAL Initiative (Helping to End Addiction Long-term Initiative). The UC San Francisco Department of Radiology and Biomedical Imaging is pleased to announce that one such project is the Back Pain Consortium (BACPAC) Research Program of which Sharmila Majumdar, PhD, vice chair for Research, is a part of. At this time, chronic low back pain is one of the most common forms of chronic pain in adults, and current treatments are ineffective, leading to increased use of opioids. This research will also lay the foundation for NIH funded research at the newly established Center for Intelligent Imaging, using artificial intelligence fueled algorithms for fast image acquisition, data analysis, quantitative sensory assessments, brain imaging, and biomechanical evaluation of the spine.